---
_id: '5369'
alternative_id:
- '5398'
article_number: '2100088'
author:
- first_name: Mario
  full_name: Lederle, Mario
  last_name: Lederle
- first_name: Mircea
  full_name: Tric, Mircea
  last_name: Tric
- first_name: Tatjana
  full_name: Roth, Tatjana
  last_name: Roth
- first_name: Lina
  full_name: Schütte, Lina
  last_name: Schütte
- first_name: Anke
  full_name: Rattenholl, Anke
  id: '202382'
  last_name: Rattenholl
  orcid: 0009-0003-6828-5778
  orcid_put_code_url: https://api.orcid.org/v2.0/0009-0003-6828-5778/work/176557802
- first_name: Dirk
  full_name: Lütkemeyer, Dirk
  last_name: Lütkemeyer
- first_name: Stefan
  full_name: Wölfl, Stefan
  last_name: Wölfl
- first_name: Tobias
  full_name: Werner, Tobias
  last_name: Werner
- first_name: Philipp
  full_name: Wiedemann, Philipp
  last_name: Wiedemann
citation:
  alphadin: '<span style="font-variant:small-caps;"><span style="font-variant:small-caps;">Lederle,
    Mario</span> ; <span style="font-variant:small-caps;">Tric, Mircea</span> ; <span
    style="font-variant:small-caps;">Roth, Tatjana</span> ; <span style="font-variant:small-caps;">Schütte,
    Lina</span> ; <span style="font-variant:small-caps;">Rattenholl, Anke</span> ;
    <span style="font-variant:small-caps;">Lütkemeyer, Dirk</span> ; <span style="font-variant:small-caps;">Wölfl,
    Stefan</span> ; <span style="font-variant:small-caps;">Werner, Tobias</span> ;
    u. a.</span>: Continuous optical in‐line glucose monitoring and control in CHO
    cultures contributes to enhanced metabolic efficiency while maintaining darbepoetin
    alfa product quality. In: <i>Biotechnology Journal</i> Bd. 16, Wiley (2021), Nr. 8'
  ama: Lederle M, Tric M, Roth T, et al. Continuous optical in‐line glucose monitoring
    and control in CHO cultures contributes to enhanced metabolic efficiency while
    maintaining darbepoetin alfa product quality. <i>Biotechnology Journal</i>. 2021;16(8).
    doi:<a href="https://doi.org/10.1002/biot.202100088">10.1002/biot.202100088</a>
  apa: Lederle, M., Tric, M., Roth, T., Schütte, L., Rattenholl, A., Lütkemeyer, D.,
    … Wiedemann, P. (2021). Continuous optical in‐line glucose monitoring and control
    in CHO cultures contributes to enhanced metabolic efficiency while maintaining
    darbepoetin alfa product quality. <i>Biotechnology Journal</i>, <i>16</i>(8).
    <a href="https://doi.org/10.1002/biot.202100088">https://doi.org/10.1002/biot.202100088</a>
  bibtex: '@article{Lederle_Tric_Roth_Schütte_Rattenholl_Lütkemeyer_Wölfl_Werner_Wiedemann_2021,
    title={Continuous optical in‐line glucose monitoring and control in CHO cultures
    contributes to enhanced metabolic efficiency while maintaining darbepoetin alfa
    product quality}, volume={16}, DOI={<a href="https://doi.org/10.1002/biot.202100088">10.1002/biot.202100088</a>},
    number={82100088}, journal={Biotechnology Journal}, publisher={Wiley}, author={Lederle,
    Mario and Tric, Mircea and Roth, Tatjana and Schütte, Lina and Rattenholl, Anke
    and Lütkemeyer, Dirk and Wölfl, Stefan and Werner, Tobias and Wiedemann, Philipp},
    year={2021} }'
  chicago: Lederle, Mario, Mircea Tric, Tatjana Roth, Lina Schütte, Anke Rattenholl,
    Dirk Lütkemeyer, Stefan Wölfl, Tobias Werner, and Philipp Wiedemann. “Continuous
    Optical In‐line Glucose Monitoring and Control in CHO Cultures Contributes to
    Enhanced Metabolic Efficiency While Maintaining Darbepoetin Alfa Product Quality.”
    <i>Biotechnology Journal</i> 16, no. 8 (2021). <a href="https://doi.org/10.1002/biot.202100088">https://doi.org/10.1002/biot.202100088</a>.
  ieee: M. Lederle <i>et al.</i>, “Continuous optical in‐line glucose monitoring and
    control in CHO cultures contributes to enhanced metabolic efficiency while maintaining
    darbepoetin alfa product quality,” <i>Biotechnology Journal</i>, vol. 16, no.
    8, 2021.
  mla: Lederle, Mario, et al. “Continuous Optical In‐line Glucose Monitoring and Control
    in CHO Cultures Contributes to Enhanced Metabolic Efficiency While Maintaining
    Darbepoetin Alfa Product Quality.” <i>Biotechnology Journal</i>, vol. 16, no.
    8, 2100088, Wiley, 2021, doi:<a href="https://doi.org/10.1002/biot.202100088">10.1002/biot.202100088</a>.
  short: M. Lederle, M. Tric, T. Roth, L. Schütte, A. Rattenholl, D. Lütkemeyer, S.
    Wölfl, T. Werner, P. Wiedemann, Biotechnology Journal 16 (2021).
date_created: 2025-01-23T15:14:34Z
date_updated: 2026-03-17T15:29:17Z
doi: 10.1002/biot.202100088
intvolume: '        16'
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
oa: '1'
publication: Biotechnology Journal
publication_identifier:
  eissn:
  - 1860-7314
  issn:
  - 1860-6768
publication_status: published
publisher: Wiley
status: public
title: Continuous optical in‐line glucose monitoring and control in CHO cultures contributes
  to enhanced metabolic efficiency while maintaining darbepoetin alfa product quality
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: '220548'
volume: 16
year: '2021'
...