https://www.hsbi.de/publikationsserver 2000-01-01T00:00+00:00 1 weekly https://www.hsbi.de/publikationsserver/record/6366 Velten, Julia Hirschfeld, Gerrit Margraf, Jürgen 2025 Low sexual desire is a common sexual problem among women. When it is accompanied by significant personal distress, it may be diagnosed as hypoactive sexual desire dysfunction (HSDD). Both cognitive behavioral therapy (CBT) and mindfulness-based therapy (MBT) are effective treatments for HSDD when delivered in person or online. In this randomized controlled treatment study, CBT and MBT consisted of eight guided self-help modules delivered online, and participants completed measures at pretreatment and after 3, 6, and 12 months. Nine variables were examined as potential mediators of treatment outcomes (i.e., sexual desire and sexual distress), namely mindfulness, self-compassion, rumination, body connection, self-consciousness, relationship satisfaction, sexual communication, depression, and anxiety. In total, 212 women diagnosed with HSDD were randomized to either CBT or MBT (Mage = 36.3, SD = 10.2). Improvements in self-compassion, rumination, body connection, and self-consciousness partially mediated treatment outcomes in at least one of the treatment groups. Mediation effects were mostly small, explaining up to 15% of the total effects. No systematic differences in mediation pathways between CBT and MBT were found. These findings emphasize the importance of emotion regulation, metacognitive processes, and embodiment for the effective treatment of HSDD. Future research should refine treatment components to enhance efficacy and ensure that psychological interventions adequately address common concerns among women with HSDD. https://www.hsbi.de/publikationsserver/record/6366 eng Informa UK Limited info:eu-repo/semantics/altIdentifier/doi/10.1080/00224499.2025.2585522 info:eu-repo/semantics/altIdentifier/issn/0022-4499 info:eu-repo/semantics/altIdentifier/issn/1559-8519 info:eu-repo/semantics/openAccess Velten J, Hirschfeld G, Margraf J. Mediators of Change in Cognitive Behavioral and Mindfulness-Based Online-Interventions for Hypoactive Sexual Desire Dysfunction in Women. <i>The Journal of Sex Research</i>. 2025:1-14. doi:<a href="https://doi.org/10.1080/00224499.2025.2585522">10.1080/00224499.2025.2585522</a> Mediators of Change in Cognitive Behavioral and Mindfulness-Based Online-Interventions for Hypoactive Sexual Desire Dysfunction in Women info:eu-repo/semantics/article doc-type:article text http://purl.org/coar/resource_type/c_6501