Data from the Researcher Mental Health Observatory STAIRCASE Survey The data presented here derives from the Sustainable Working Conditions in Academia survey (STAIRCASE) on researcher mental health. The survey addresses the ongoing mental health crisis in academia by providing comprehensive, multilevel data on researcher well-being and its structural determinants. We employed a cross-sectional between-participant study design to collect data from 4,296 researchers between September 15, 2023, and August 26, 2024. The sample, which primarily includes researchers based in European countries, has a mean age of 38.1 years (SD = 10.7) and consists of 63.7% female participants. Participants provided data on key mental health outcomes – including depression, anxiety, stress, burnout, and well-being – alongside detailed assessments of working conditions, leadership behavior, and organizational characteristics. The dataset facilitates a holistic, multilevel investigation of academic mental health beyond individual risk factors by including the individual, leadership, institutional, and national context. By enabling analyses across hierarchical levels this dataset provides the necessary evidence to identify systemic drivers of mental (ill) health and inform the development of effective, system-wide strategies for meaningful change in academic work environments. 14 1 Ubiquity Press, Ltd. application/pdf