---
res:
  bibo_abstract:
  - "                  Chemoenzymatic processes have been gaining interest to implement
    sustainable reaction steps or even create new synthetic routes. In this study,
    we combined Grubbs’ second-generation catalyst with pig liver esterase and conducted
    a chemoenzymatic one-pot process in a tandem mode. To address sustainability,
    we encapsulated the catalysts in biopolymer hydrogel beads and conducted the reaction
    cascade in an aqueous medium. Unfortunately, conducting the process in tandem
    led to increased side product formation. We then created core-shell beads with
    catalysts located in different compartments, which notably enhanced the selectivity
    towards the desired product compared to homogeneously distributing both catalysts
    within the matrix. Finally, we designed a specific large-sized bead with a diameter
    of 13.5 mm to increase the diffusion route of the Grubbs’ catalyst-containing
    shell. This design forced the ring-closing metathesis to occur first before the
    substrate could diffuse into the pig liver esterase-containing core, thus enhancing
    the selectivity to 75%. This study contributes to addressing reaction-related
    issues by designing specific immobilisates for chemoenzymatic processes.\r\n                @eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Jan
      foaf_name: Pauly, Jan
      foaf_surname: Pauly
  - foaf_Person:
      foaf_givenName: Harald
      foaf_name: Gröger, Harald
      foaf_surname: Gröger
  - foaf_Person:
      foaf_givenName: 'Anant V. '
      foaf_name: 'Patel, Anant V. '
      foaf_surname: Patel
      foaf_workInfoHomepage: http://www.librecat.org/personId=201870
  bibo_doi: 10.3390/catal9060547
  bibo_issue: '6'
  bibo_volume: 9
  dct_date: 2019^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2073-4344
  dct_language: eng
  dct_publisher: MDPI@
  dct_title: Developing Multicompartment Biopolymer Hydrogel Beads for Tandem Chemoenzymatic
    One-Pot Process@
...